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单边直线感应电机 2

线性规划 2

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FLTD型脉冲加速器 1

H∞控制；零和动态博弈；强化学习；自适应动态规划；极小极大Q-学习；策略迭代 1

PCI总线 1

Weibull分布杂波 1

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中断模型；k-可靠性；对偶；线性规划松弛；互补松弛型 1

中空纤维膜，膜材料，膜应用，可持续和高质量发展 1

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二维线性鉴别分析 1

人脸建模 1

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仿真 1

倾转旋翼机；状态跟踪控制；线性切换系统；类时间依赖的多Lyapunov函数方法；光滑插值 1

像融合；分数阶导数；直觉模糊集；多聚焦图像 1

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Optical performance analysis of an innovative linear focus secondary trough solar concentrating system

Xiliang ZHANG, Zhiying CUI, Jianhan ZHANG, Fengwu BAI, Zhifeng WANG

《能源前沿（英文）》 2019年 第13卷 第3期   页码 590-596 doi: 10.1007/s11708-018-0602-y

摘要： The parabolic trough solar concentrating system has been well developed and widely used in commercial solar thermal power plants. However, the conventional system has its drawbacks when connecting receiver tube parts and enhancing the concentration ratio. To overcome those inherent disadvantages, in this paper, an innovative concept of linear focus secondary trough concentrating system was proposed, which consists of a fixed parabolic trough concentrator, one or more heliostats, and a fixed tube receiver. The proposed system not only avoids the end loss and connection problem on the receiver during the tracking process but also opens up the possibility to increase the concentration ratio by enlarging aperture. The design scheme of the proposed system was elaborated in detail in this paper. Besides, the optical performance of the semi and the whole secondary solar trough concentrator was evaluated by using the ray tracing method. This innovative solar concentrating system shows a high application value as a solar energy experimental device.

关键词： secondary parabolic trough solar concentrator     ray tracing method     linear focus     concentration ratio     optical performance    

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Metformin and metabolic diseases: a focus on hepatic aspects

null

《医学前沿（英文）》 2015年 第9卷 第2期   页码 173-186 doi: 10.1007/s11684-015-0384-0

摘要：

Metformin has been widely used as a first-line anti-diabetic medicine for the treatment of type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses hepatic glucose production (HGP), serving as the main mechanism by which metformin improves hyperglycemia of T2D. Biochemically, metformin suppresses gluconeogenesis and stimulates glycolysis. Metformin also inhibits glycogenolysis, which is a pathway that critically contributes to elevated HGP. While generating beneficial effects on hyperglycemia, metformin also improves insulin resistance and corrects dyslipidemia in patients with T2D. These beneficial effects of metformin implicate a role for metformin in managing non-alcoholic fatty liver disease. As supported by the results from both human and animal studies, metformin improves hepatic steatosis and suppresses liver inflammation. Mechanistically, the beneficial effects of metformin on hepatic aspects are mediated through both adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. In addition, metformin is generally safe and may also benefit patients with other chronic liver diseases.

关键词： metformin     diabetes     hepatic steatosis     inflammatory response     insulin resistance    

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Energy and economic analysis of a point-focus concentrating photovoltaic system when its installation

C. RENNO, A. PERONE

《能源前沿（英文）》 2021年 第15卷 第2期   页码 384-395 doi: 10.1007/s11708-020-0717-9

摘要： The concentrating photovoltaic (CPV) systems are a promising technology to obtain clean energy. However, these systems are not equally convenient worldwide due to different climatic conditions. The main aim of this paper is to analyze energy and economic performances of a point-focus CPV system for a residential user when its installation site varies. Three locations, Riyadh, Copenhagen, and Palermo, characterized by very different weather conditions are chosen. A model that links the electrical power of a triple-junction (TJ) cell with its temperature and concentrated radiation incident on it is experimentally developed to evaluate the energy performance of the CPV system. A comparison of the three localities for typical winter and summer sunny days indicates that the higher values of the TJ cell temperature are reached in summer, over 70°C at Riyadh, and its electrical power is reduced compared to a winter day. In winter, a TJ cell in Riyadh supplies an electric power of about 20% higher than that in other two cities, while in summer, the maximum power is observed at Copenhagen. On the contrary, the electrical producibility also depends on the sunlight daily hours number during the year. Hence, considering the real distribution of direct normal irradiance (DNI) and the environmental temperature for each locality, a CPV system composed of modules of 90 cells adopted for a residential user is sized. The electric producibility of the CPV system, by varying its module number, is evaluated for different localities together with the optimal number of the modules which is able to maximize the investment profitability.

关键词： CPV system     point-focus     experimental model     energy and economic analysis    

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Review of aeroelasticity for wind turbine: Current status, research focus and future perspectives

Pinting ZHANG, Shuhong HUANG

《能源前沿（英文）》 2011年 第5卷 第4期   页码 419-434 doi: 10.1007/s11708-011-0166-6

摘要： Aeroelasticity has become a critical issue for Multi-Megawatt wind turbine due to the longer and more flexible blade. In this paper, the development of aeroelasticity and aeroelastic codes for wind turbine is reviewed and the aeroelastic models for wind turbine blade are described, based on which, the current research focuses for large scale wind turbine are discussed, including instability problems for onshore and offshore wind turbines, effects of complex inflow, nonlinear effects of large blade deflection, smart structure technologies, and aerohydroelasticity. Finally, the future development of aeroelastic code for large scale wind turbine: aeroservoelasticity and smart rotor control; nonlinear aeroelasticity due to large blade deflection; full-scale 3D computational fluid dynamics (CFD) solution for dynamics; and aerohydroelasticity are presented.

关键词： wind turbine     aeroelasticity     aeroelastic code    

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Current scenario and challenges of plastic pollution in Bangladesh: a focus on farmlands and terrestrial

《环境科学与工程前沿（英文）》 2023年 第17卷 第6期 doi: 10.1007/s11783-023-1666-4

摘要：

● A global snapshot of plastic waste generation and disposal is analysed.

关键词： Plastic waste     Farmlands     Terrestrial ecosystem     Marine life    

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Blockchain-based smart contract for smart payment in construction: A focus on the payment freezing and

《工程管理前沿（英文）》 2022年 第9卷 第2期   页码 177-195 doi: 10.1007/s42524-021-0184-y

摘要： Late payment, and indeed no payment, is a rampant and chronic problem that has plagued the global construction industry for too long. Recent development in blockchain technology, particularly its smart contract, seems to provide a new opportunity to improve this old problem. However, this opportunity is largely unexploited. This study aims to develop a blockchain-based smart contract (BBSC) system for smart payment in the construction industry by focusing on the fundamental cycle of payment freezing (sometimes also synonymously called payment guarantees) and disbursement application. Firstly, a BBSC framework, containing three processes of (a) initiation and configuration, (b) payment freezing, and (c) disbursement application, is developed. Next, based on the framework, the system architecture of the BBSC system, containing three layers of (1) Infrastructure as a Service (IaaS), (2) Blockchain as a Service (BaaS), and (3) Software as a Service (SaaS) is proposed and elaborated. Finally, based on the system architecture, a BBSC prototype system is developed using a real-life modular construction project as a case study. It was found that the prototype system can improve the certainty and efficiency of the progress payment, thereby enabling smart payment in construction transactions. Without advocating radical changes (e.g., the contractual relationships or the intermediate role of banks in modern construction projects), the prototype can be developed into a real-life BBSC system that can work compatibly with current advancements in the field. Future works are recommended to fine-tune the findings and translate and implement them in real-life applications.

关键词： blockchain     construction project     smart contract     smart payment     payment dispute    

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Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)

《医学前沿（英文）》 doi: 10.1007/s11684-023-1037-3

摘要： The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous efforts to develop therapeutic agents that target severe acute respiratory syndrome coronavirus 2 to control viral infection. So far, a few small-molecule antiviral drugs, including nirmatrelvir–ritonavir (Paxlovid), remdesivir, and molnupiravir have been marketed for the treatment of COVID-19. Nirmatrelvir–ritonavir has been recommended by the World Health Organization as an early treatment for outpatients with mild-to-moderate COVID-19. However, the existing treatment options have limitations, and effective treatment strategies that are cost-effective and convenient for tackling COVID-19 are still needed. To date, four domestically developed oral anti-COVID-19 drugs have been granted conditional market approval in China. These drugs include azvudine, simnotrelvir–ritonavir (Xiannuoxin), leritrelvir, and mindeudesivir (VV116). Preclinical and clinical studies have explored the efficacy and tolerability of mindeudesivir and supported its early use in mild-to-moderate COVID-19 cases at high risk for progression. In this review, we discuss the most recent findings regarding the pharmacological mechanism and therapeutic effects focusing on mindeudesivir and other small-molecule antiviral agents for COVID-19. These findings will expand our understanding and highlight the potential widespread application of China’s homegrown anti-COVID-19 drugs.

关键词： COVID-19     antiviral drugs     mindeudesivir    

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Design and analysis of linear oscillating motor for linear pump application-magnetic field, dynamics

Zongxia JIAO,Tianyi WANG,Liang YAN

《机械工程前沿（英文）》 2016年 第11卷 第4期   页码 351-362 doi: 10.1007/s11465-016-0407-9

摘要：

A linear oscillating motor is an electromagnetic actuator that can achieve short-stroke reciprocating movement directly without auxiliary transmission mechanisms. It has been widely used in linear pump applications as the source of power and motion. However, because of the demand of high power density in a linear actuation system, the performance of linear oscillating motors has been the focus of studies and deserves further research for high power density. In this paper, a general framework of linear oscillating motor design and optimization is addressed in detail, including the electromagnetic, dynamics, and thermal aspects. First, the electromagnetic and dynamics characteristics are modeled to reveal the principle for optimization. Then, optimization and analysis on magnetic structure, resonant system, and thermal features are conducted, which provide the foundation for prototype development. Finally, experimental results are provided for validation. As a whole, this process offers complete guidance for high power density linear oscillating motors in linear pump applications.

关键词： linear oscillating motor     linear pump     magnetic field     motor optimization    

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Comparison between linear and non-linear forms of pseudo-first-order and pseudo-second-order adsorption

Junxiong LIN , Lan WANG ,

《环境科学与工程前沿（英文）》 2009年 第3卷 第3期   页码 320-324 doi: 10.1007/s11783-009-0030-7

摘要： The best-fit equations of linear and non-linear forms of the two widely used kinetic models, namely pseudo-first-order and pseudo-second-order equations, were compared in this study. The experimental kinetics of methylene blue adsorption on activated carbon was used for this research. Both the correlation coefficient () and the normalized standard deviation Δ(%) were employed as error analysis methods to determine the best-fitting equations. The results show that the non-linear forms of pseudo-first-order and pseudo-second-order models were more suitable than the linear forms for fitting the experimental data. The experimental kinetics may have been distorted by linearization of the linear kinetic equations, and thus, the non-linear forms of kinetic equations should be primarily used to obtain the adsorption parameters. In addition, the Δ(%) method for error analysis may be better to determine the best-fitting model in this case.

关键词： adsorption     pseudo-first order     pseudo-second order     kinetic model     linear method     non-linear method    

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聚焦两相界面

沈平

《工程（英文）》 2021年 第7卷 第5期   页码 552-553 doi: 10.1016/j.eng.2021.02.003

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Improving the efficiency and effectiveness of global phosphorus use: focus on root and rhizosphere levels

null

《农业科学与工程前沿（英文）》 2019年 第6卷 第4期   页码 357-365 doi: 10.15302/J-FASE-2019275

摘要：

Phosphorus (P) is essential for life and for efficient crop production, but global P use with limited recycling is inefficient in several sectors, including agronomy. Unfortunately, plant physiologists, agronomists, farmers and end users employ different measures for P use efficiency (PUE), which often masks their values at different scales. The term P use effectiveness, which also considers energetic and sustainability measures in addition to P balances, is also a valuable concept. Major physiological and genetic factors for plant P uptake and utilization have been identified, but there has been limited success in genetically improving PUE of modern crop cultivars. In maize, studies on root architectural and morphological traits appear promising. Rhizosphere processes assist in mobilizing and capturing sparingly soluble phosphate from rock phosphate. Combinations of phosphate-solubilizing microorganisms with ammonium-based nitrogen fertilizer, as well as strategies of fertilizer placement near the roots of target crops, can moderately enhance PUE. The desired concentration of P in the products differs, depending on the final use of the crop products as feed, food or for energy conversion, which should be considered during crop production.

关键词： acquisition efficiency     plant growth promoting rhizobacteria     phosphate     use efficiency     utilization efficiency    

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FOR USE IN AGROECOSYSTEM IMPROVEMENT IN SEMI-ARID AREAS WITH A FOCUS ON CENTRAL ANATOLIA, TURKEY

《农业科学与工程前沿（英文）》 2021年 第8卷 第4期   页码 568-582 doi: 10.15302/J-FASE -2019270

摘要：

Agroecosystems in water-limited contexts— Mediterranean, semi-arid and arid climatic zones—are too frequently degraded systems that will not provide the needed ecosystem services to ensure a future of sustainable agricultural production. The processes that have created this situation continue and are being accelerated by anthropogenic climate change. Increasing arboreal vegetation in these areas through agroforestry is an important strategy to conserve and improve their agroecosystems. Actinorhizal trees and shrubs in the Casurinaceae have a unique set of adaptations for heat and water stress, and/or infertile to hostile soils. Central Anatolia, Turkey is particularly at risk of increasing aridity and further degradation. Therefore, species of Allocasuarina and Casuarina have been evaluated for their potential use in agroecosystem improvement in semi-arid areas with a focus on Central Anatolia. Based on a semiquantitative environmental tolerance index and reported plant stature, eight species were identified as being of high (A. verticillata and C. pauper) to moderate (A. acutivalvis, A. decaisneana, A. dielsiana, A. huegeliana, C. cristata and C. obesa) priority for assessment, with none of these species having been adequately evaluated for agroforestry deployment in semi-arid agroecosystems in any context.

 

关键词： actinorrhizal trees / agroforestry / climate change / ecosystem restoration    

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Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

null

《医学前沿（英文）》 2013年 第7卷 第2期   页码 231-241 doi: 10.1007/s11684-013-0253-7

摘要：

Hepatocellular carcinoma (HCC) development is characterized by the presence of epigenetic alterations, including promoter DNA hypermethylation and post-translational modifications of histone, which profoundly affect expression of a wide repertoire of genes critical for cancer development. Emerging data suggest that deregulation of polycomb group (PcG) proteins, which are key chromatin modifiers repressing gene transcription during developmental stage, plays a causative role in oncogenesis. PcG proteins assemble into polycomb repressive complex 1 (PRC1) and polycomb repressive complex 2 (PRC2) to impose the histone H3 lysine 27 trimethylation (H3K27me3) modification for repression. In this review, we will first recapitulate the mechanisms of two key epigenetic pathways: DNA methylation and histone modifications. Specifically, we will focus our discussion on the molecular roles of PcG proteins. Next, we will highlight recent findings on PcG proteins, their clinicopathological implication and their downstream molecular consequence in hepatocarcinogenesis. Last but not least, we will consider the therapeutic potential of targeting enhancer of zeste homolog 2 (EZH2) as a possible treatment for HCC. Improving our understanding on the roles of PcG proteins in hepatocarcinogenesis can benefit the development of epigenetic-based therapy.

关键词： liver cancer     epigenetics     histone modifications     polycomb group proteins     enhancer of zeste homolog 2 (EZH2)    

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General expression for linear and nonlinear time series models

Ren HUANG, Feiyun XU, Ruwen CHEN

《机械工程前沿（英文）》 2009年 第4卷 第1期   页码 15-24 doi: 10.1007/s11465-009-0015-z

摘要： The typical time series models such as ARMA, AR, and MA are founded on the normality and stationarity of a system and expressed by a linear difference equation; therefore, they are strictly limited to the linear system. However, some nonlinear factors are within the practical system; thus, it is difficult to fit the model for real systems with the above models. This paper proposes a general expression for linear and nonlinear auto-regressive time series models (GNAR). With the gradient optimization method and modified AIC information criteria integrated with the prediction error, the parameter estimation and order determination are achieved. The model simulation and experiments show that the GNAR model can accurately approximate to the dynamic characteristics of the most nonlinear models applied in academics and engineering. The modeling and prediction accuracy of the GNAR model is superior to the classical time series models. The proposed GNAR model is flexible and effective.

关键词： linear and nonlinear     autoregressive model     system identification     time series analysis    

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氢动力——从小型汽车到重型交通工具

Chris Palmer

《工程（英文）》 2020年 第6卷 第12期   页码 1333-1335 doi: 10.1016/j.eng.2020.10.006

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标题 作者 时间 类型 操作

Optical performance analysis of an innovative linear focus secondary trough solar concentrating system

Xiliang ZHANG, Zhiying CUI, Jianhan ZHANG, Fengwu BAI, Zhifeng WANG

期刊论文

Metformin and metabolic diseases: a focus on hepatic aspects

null

期刊论文

Energy and economic analysis of a point-focus concentrating photovoltaic system when its installation

C. RENNO, A. PERONE

期刊论文

Review of aeroelasticity for wind turbine: Current status, research focus and future perspectives

Pinting ZHANG, Shuhong HUANG

期刊论文

Current scenario and challenges of plastic pollution in Bangladesh: a focus on farmlands and terrestrial

期刊论文

Blockchain-based smart contract for smart payment in construction: A focus on the payment freezing and

期刊论文

Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)

期刊论文

Design and analysis of linear oscillating motor for linear pump application-magnetic field, dynamics

Zongxia JIAO,Tianyi WANG,Liang YAN

期刊论文

Comparison between linear and non-linear forms of pseudo-first-order and pseudo-second-order adsorption

Junxiong LIN , Lan WANG ,

期刊论文

聚焦两相界面

沈平

期刊论文

Improving the efficiency and effectiveness of global phosphorus use: focus on root and rhizosphere levels

null

期刊论文

FOR USE IN AGROECOSYSTEM IMPROVEMENT IN SEMI-ARID AREAS WITH A FOCUS ON CENTRAL ANATOLIA, TURKEY

期刊论文

Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

null

期刊论文

General expression for linear and nonlinear time series models

Ren HUANG, Feiyun XU, Ruwen CHEN

期刊论文

氢动力——从小型汽车到重型交通工具

Chris Palmer

期刊论文